Mike Piazza -- June 14, 2001 -- 447 feet

SportsFootballBaseballMike PiazzaJosh TowersOriole Park at Camden YardsSt. Louis Cardinals
New York Mets catcher Mike Piazza drives an RBI single to center in the first inning against the St. Louis Cardinals in 2002. On June 14, 2001, Piazza hit a 447-foot solo home run against Orioles starting pitcher Josh Towers at Camden Yards. Getty Images