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The White Sox's offense did its best Tuesday night to come to the rescue of its once-invincible pitching staff.
But uncharacteristically poor pitching and shoddy defense finally caught up to the Sox in a 9-7 loss at Oakland.
A dropped fly ball by right fielder Jermaine Dye paved the way for two Oakland runs in the eighth inning. The Sox blew a pair of three-run leads as Mark Buehrle blew a chance for his fourth victory.
The loss snapped the Sox's eight-game winning streak. The Athletics took the lead for good when pinch-hitter Erubiel Durazo hit a grounder that went under the glove of shortstop Willie Harris for what was ruled a hit.
Harris was making his first major-league appearance at shortstop because Pablo Ozuna had to leave the game in the bottom of the seventh after getting struck on the left hand by a pitch in the top of the inning and went for X-rays.
"It was kind of a funky game," White Sox manager Ozzie Guillen said.
Buehrle was knocked out in the seventh. He managed to pitch at least six innings for his 33rd consecutive start, but he was roughed up for seven runs on 11 hits and was pulled during the midst of Oakland's three-run seventh that tied it.
Damaso Marte committed a balk that allowed Eric Chavez to score from third, making the score 7-7. Third-base umpire Jerry Meals ruled that Marte started from the stretch position but broke his hands while stepping off the rubber.
In addition to Ozuna's injury, shortstop Juan Uribe had to leave the game in the top of the seventh after hurting his groin while taking a pitch for a 3-0 count.
Third baseman Joe Crede, who was scratched from the starting lineup because of a sore left foot, finished Uribe's at-bat and drew a walk.
Designated hitter Carl Everett was struck in the back by a pitch from Oakland starter Rich Harden in the fifth inning with the Sox leading 3-0.
Everett glared at Harden for several seconds before walking to first base. Home plate umpire and crew chief Bruce Froemming issued warnings to both benches.
The Sox had no problems solving Harden, who entered Tuesday's game with a 15-inning scoreless streak and 0.44 ERA.
They tagged Harden, who had allowed only one earned run in 20 1/3 innings, for six runs in 5 1/3 innings.
Every Sox player in the starting lineup except No. 9 hitter Ozuna had at least one hit.
The Sox entered the game with a .213 batting average with runners in scoring position but came through often against Harden.
Consecutive singles by Tadahito Iguchi, Everett and Paul Konerko in the first inning gave the Sox a 1-0 lead, extending their streak of leading in all of their 21 games this season.
In the fourth, Dye hit his first double of the season, and Aaron Rowand, Uribe and Chris Widger followed with singles to extend the Sox's lead to 3-0.
But Buehrle couldn't hold the lead. The Athletics snapped a streak of 26 scoreless innings with a four-run fifth. Oakland, which ranked last in the league with a .201 batting average with runners in scoring position, came through with clutch hits.
"It's just an embarrassing game all around," said Buehrle. "I should've gone out there and stopped them and we should have won this game."
Chavez, who was 1 for 21 with runners in scoring position, hit a two-run single that tied the game 3-3.
The Sox regained the lead with a four-run sixth, capped by Iguchi's two-run single off Keiichi Yabu in a showdown of Japanese imports.
"I don't think many people are going to put their heads down," Rowand said. "It was just an all-out weird game. I've never seen anything quite like that, so it's not like we went out and played well and lost a heartbreaker."
Associated Press contributed to this report.