Six's extension keeps him at Hampton through the 2018-19 season. Terms were not disclosed.
"I am extremely excited to about the opportunity to lead the Lady Pirates for five more years," Six said in a statement released by the athletic department. "I am also appreciative of the commitment and the support for me and my family from the university administration — in particular Dr. (William) Harvey and Mr. (Novelle) Dickenson.
"My journey started here at Hampton; it has been rewarding and I have been blessed. However, there still remains some unfinished business and I look forward to the challenge."
Six is 99-30 in four years at HU, 58-6 in Mid-Eastern Athletic Conference play, and his teams have won all four MEAC tournament titles.
Hampton (28-6) won a school record 28 games last season and became the first HU women's team to go unbeaten (16-0) in the conference, earning him his second Coach of the Year award. The Lady Pirates' current string of four consecutive MEAC titles matches Howard for the most in the history of the conference.
Hampton led the nation in scoring defense last season (47.8 ppg) and was third in field goal percentage defense and 3-point field goal defense.
Six built a prep power at Hampton High before he took a job in the HU athletic department. He spent one year in the position, then replaced former coach Walter Mebane on an interim basis. The interim tag was removed after the Lady Pirates' first MEAC title and NCAA berth.