SAG National President Ken Howard said in a statement Wednesday that Borgnine has boundless energy "which, at 93, is still a hallmark of his remarkably busy life and career."
He has appeared in more than 200 movies. He won a best-actor Oscar for his performance in the 1955 film "Marty."
His TV credits include the 1960s series "McHale's Navy." He was nominated for an Emmy for his guest role last year in the final episode of "ER."
He will receive the award for career achievement and humanitarian accomplishment at the 17th annual SAG Awards in Los Angeles on Jan. 30, 2011.