The futuristic fantasy is expected to bring $50 million over the four-day holiday, according to people familiar with pre-release audience surveys.
"Poltergeist," a new offering from Twentieth Century Fox and MGM, could open with between $20 million to $30 million. But Marvel's "Avengers: Age of Ultron" could potentially surpass the horror film and nab the No. 4 spot. Tracking suggests the superhero sequel could add around $25 million to its robust domestic haul of about $378.5 million.
Overall, the domestic box office is looking at a less robust haul over the holiday weekend than in previous years.
To date, "Pirates of the Caribbean: At World's End" -- like "Tomorrowland," another Disney film inspired by the company's theme parks -- holds the Memorial Day weekend record. It opened in 2007 with $139.8 million in the U.S. and Canada. Last year,
"Tomorrowland," which cost $170 million to make, will likely appeal to family audiences looking for PG-rated counterprogramming.
Directed by Brad Bird, the film follows teenager Casey (up-and-coming young actress Britt Robertson) as she embarks on a journey with former boy-genius Frank (George Clooney) to unearth secrets of a place known as Tomorrowland.
Reviews for the film have been mixed, with critics giving it a lukewarm 56% positive rating on Rotten Tomatoes. It begins rolling out in theaters Thursday evening and will also open in 65 international markets this weekend.
With a fervent fan base, "Pitch Perfect 2" is likely going to come in second. Female filmgoers flexed their box-office might last weekend, helping the Universal Pictures film surpass expectations with a $69.2 million opening.
In the sequel, which cost $29 million to make, Anna Kendrick, Rebel Wilson and Brittany Snow reprise their roles as members of the college a cappella group the Barden Bellas. Audiences polled by CinemaScore gave it an A-minus rating.
The latest George Miller franchise film earned an impressive 98% fresh rating on Rotten Tomatoes and a B-plus from viewers polled by CinemaScore. The film stars Tom Hardy, in the title role made famous by
Though "Poltergeist" has not been well-recieved by critics (it earned a 31% positive rating on Rotten Tomatoes), horror films usually fare well at the box office.
The film, which cost $35 million to make, is a reboot of the 1982 favorite. Directed by Gil Kenan, new movie stars Sam Rockwell and Rosemarie DeWitt. Fox has a more modest projection of $20 million to $22 million for the debut.
Lower weekend totals won't necessarily put a dent in the industry. As of Sunday, the box office was up an estimated 5.8% year-to-date, according to research firm Rentrak.
The summer slate includes anticipated blockbusters such as "Jurassic World," "Terminator: Genisys," "Ant-Man" and "Fantastic Four," as well as female-driven flicks such as "Spy," "Magic Mike XXL" and "Paper Towns."