Abruptly departed: Shannen Doherty Played: Brenda Walsh Lasted: Four years (1990-94) Why she left: Doherty was reportedly as difficult on the set as she was off the set. When alleged clashes ensued between Doherty and Jennie Garth, she and the producers had a sit-down and all parties agreed that Doherty should leave. How it went down on air: After her first year at college, Brenda moved to London to pursue her acting career at the Royal Academy for Dramatic Arts and was never heard from again.
Andrew Semel / FOX
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