Look back: 25 great 'Oprah' moments

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Oprah WinfreyLiberace's last TV appearance (1986)Racism in Forsyth County (1987)Oprah sheds light on the AIDS crisis (1987)'Diet Dreams Come True' (1988)Michael Jackson interview (1993)Oprah's Book Club launches (1996)Oprah's mad cow problem (1996)Ellen DeGeneres comes out as a lesbian (1997)Oprah and Dr. Phil (1998)The Mattie Stepanek interview (2001)Oprah's 'Favorite Things' episode (2002)Oprah and Dr. Oz (2004)The brand-new car giveaway (2004)Tom Cruise loves Katie Holmes (2005)Tracey Gold comes clean (2005)Oprah Winfrey endorses Barack Obama (2006)James Frey is in the hot seat (2006)Roadtrip! (2006)Oprah reveals 'The Secret' (2007)Tommy Hilfiger and the racist rumor (2007)Pregnant man Thomas Beatie (2008)Mackenzie Phillips talks about incestuous relationship (2009)Surprise flash mob featuring the Black Eyed Peas (2009)Sarah Palin visits Oprah (2009)Sarah Ferguson opens up about bribery scandal (2010)

Oprah launched Oprah's Book Club, a discussion segment from "The Oprah Winfrey Show," on Sept. 17, 1996. Her first pick was "The Deep End of the Ocean" by Jacquelyn Mitchard. Since then, she's chosen 65 selections for her book club, offering members Q-and-As with authors, character guides, reading questions, quizzes and video.<br>
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The club's popularity spawned the "Oprah effect" -- when lesser-known books launch onto bestseller lists because of Winfrey.

Oprah's Book Club launches (1996)

( George Burns / Harpo Productions )

Oprah launched Oprah's Book Club, a discussion segment from "The Oprah Winfrey Show," on Sept. 17, 1996. Her first pick was "The Deep End of the Ocean" by Jacquelyn Mitchard. Since then, she's chosen 65 selections for her book club, offering members Q-and-As with authors, character guides, reading questions, quizzes and video.

The club's popularity spawned the "Oprah effect" -- when lesser-known books launch onto bestseller lists because of Winfrey.

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