Vitamin B-12 deficiency linked to acid reducers

After taking Aciphex to treat heartburn for four years, I developed a vitamin B-12 deficiency. I complained to my doctor about being tired all the time. I was also diagnosed with hypothyroidism. I had to beg to have my B-12 levels tested, because my doctor didn't think it was a problem, but found that it was.

Acid-suppressing drugs such as Aciphex, Nexium, omeprazole, Prevacid, Prilosec and Protonix relieve reflux symptoms. But there is a downside. Stomach acid is essential for absorbing nutrients such as calcium and vitamin B-12.

Cases of vitamin B-12 deficiency have been linked to acid-suppressor therapy (Journal of the American Medical Directors Assn., March). Symptoms include fatigue, confusion and memory problems, peripheral neuropathy (nerve damage that causes pain and numbness in hands and feet), constipation and depression.

Getting off acid-suppressing drugs can be challenging. Acid rebound can last for months after stopping.







I take lisinopril for high blood pressure and occasionally have a cough that cough syrup can't touch. My doctor suggested benzonatate. It works for me!

Thanks for the tip. Benzonatate (Tessalon) is not appropriate for anyone allergic to local anesthetics such as procaine (Novocain). An iron supplement also may help with this kind of cough, as may switching to another kind of blood pressure medication.

Contact Joe Graedon, a pharmacologist, and Teresa Graedon, an expert in medical anthropology and nutrition, at www.peoplespharmacy.com or care of this newspaper.