The party establishment is increasingly hopeful that the answer is yes. But mathematically, at least, the answer is clearly no.
A candidate needs to amass 1,144 delegates to clinch the nomination, and just 37 have been allocated so far based on the primaries in New Hampshire and South Carolina (Iowa has not awarded any yet based on the Jan. 3 caucuses).
Another 50 delegates are at stake in Florida's primary Tuesday, to be awarded on a winner-take all basis. And 28 delegates are up for grabs this weekend when Republicans caucus in Nevada.
Nevada, meanwhile, is one of the few early states Romney won in his 2008 campaign, and few expect the other candidates to threaten his advantage there.
While Romney may still lack a clear delegate edge by week's end, he'll be heavy with momentum. Establishment Republicans eager to move on from the intra-party squabbling can be expected to continue their pleas for the party to close ranks.
The key question then for other candidates is whether they can remain viable in what will be an unusual dead period for several weeks.
Contests on Feb. 7 in Colorado, Minnesota and Missouri will not immediately determine how those states' Republicans vote at the party's August convention. So the next real battlegrounds are Arizona and Michigan, which don't vote until Feb. 28.
Super Tuesday follows a week later, with primaries in Georgia, Massachusetts, Oklahoma, Tennessee, Vermont and Virginia, and caucuses in Idaho and North Dakota.
"We will go all the way to the convention," Gingrich told reporters Sunday. "This is going to be a straight-out contest for the next four or five months."
He also isn't ready to concede Florida, telling
"When Floridians learn that
And then, of course, there's