Reuters cited three unnamed sources in its report that Clinton was open to leaving Foggy Bottom early, should current World Bank President Robert Zoellick leave at the end of his term.
Philippe Reines, traveling with Clinton in the United Arab Emirates, said the story was "completely untrue" and "bogus."
"Secretary Clinton has not had any conversations with the president, the White House or anyone about moving to the World Bank. She has expressed absolutely no interest in the job. She would not take it if offered," Reines said in an email to reporters.
Clinton's future has long been a favorite subject in the Beltway cocktail circuit, with theories including a vice presidential run in place of Joe Biden in 2012, and another run of her own for the presidency in 2016.
In fact, Clinton has repeatedly said she looks forward to some down time at the end of President Obama's first term.