Ever since the drug
Roughly six decades after its introduction, Kcentra has been approved by the
But vitamin K takes time to work, and so does frozen plasma, which must be thawed and typed to the recipient's blood group. Kcentra does not need to be typed to the recipient's blood and so can be used more quickly to reverse the effects of warfarin.
The new agent does not, however, work to reverse the effects of two anticoagulants that are new to the market -- dabigatran (marketed as Pradaxa) or
Just over 2 million Americans are thought to have atrial fibrillation, which puts them at much higher risk of stroke, and that number is expected to grow to 5.6 million by 2050 as the population ages. Many taking warfarin are switching to the newer and more effective stroke-preventing medications, and most newly diagnosed atrial fibrillation patients appear to be prescribed them first.