Kansas used an 18-3 run in the opening minutes to silence a small but vocal section of Colorado fans, pushed the advantage to more than 20 by halftime and kept building on it throughout the second half. The lead surpassed 30 with 17 minutes left and reached the 40-point mark with about 8 minutes to go.
Josh Scott finished with 19 points to lead the Buffaloes (7-2), who have lost two of three after rattling off six straight wins to start the year. Askia Booker added 15 points, while leading scorer Spencer Dinwiddie was held to four points on 1-for-4 shooting. Xavier Johnson missed all four of his field-goal attempts before fouling out.