Headed to his first All-Star game, Irving added to his credentials by calmly draining a pull-up jumper from the top of the arc to send the Cavaliers to their third straight win.
Toronto had five players score in double figures. Amir Johnson had 18 points and 12 rebounds, Alan Anderson scored 17 and Ed Davis finished with 16.
The Raptors had won seven of their previous nine meetings with the Cavaliers.
at Philadelphia 97, New York 80: Jrue Holiday scored a career-high 35 points, Nick Young had 20 and the 76ers cruised to a victory over the Knicks. Carmelo Anthony needed 28 shots to get 25 points.
at Charlotte 102, Minnesota 101: Gerald Henderson hit a three-pointer from 25 feet with 4.6 seconds left to lift the Bobcats to a win over the Timberwolves, snapping a 16-game home losing streak. Kemba Walker led Charlotte with 25 points and Ramon Sessions finished with 23.
at Washington 86, Chicago 73: Emeka Okafor had 15 points and 16 rebounds, helping the surging Wizards beat the Bulls. Nene scored 16 points and John Wall had 15 for Washington, which has won consecutive games for the second time this season.
at Houston 119, Brooklyn 106: James Harden scored 29 points, Chandler Parsons added 16 points and a career-high 11 assists and the Rockets beat Brooklyn for their 12th consecutive win over the Nets. Nets star Deron Williams scored 27 points, but cooled off after a 20-point first quarter.
at San Antonio 108, Phoenix 99: Tony Parker had 31 points and the Spurs collected their eighth consecutive win by shutting down the Suns in the final quarter. Michael Beasley had 25 points and Jared Dudley had 23 for Phoenix, which lost for the first time since Coach Lindsey Hunter took over.
at Milwaukee 109, Golden State 102: Brandon Jennings scored 20 points to lead the Bucks to a victory over the Warriors. Milwaukee's Monta Ellis scored 20 points against his former team, while Ersan Ilyasova added 18 points and 12 rebounds. Stephen Curry led Golden State with 26 points.
at Denver 121, Sacramento 93: Ty Lawson scored 26 points, Andre Iguodala had 20 and the Nuggets used a strong first three quarters to rout the Kings. Danilo Gallinari added 14 points for the Nuggets, who led, 71-49, at intermission to set a season high for points in a half.