Coughing between points on an overcast day, the second-seeded Sharapova was outplayed throughout a 7-6 (3), 6-4 loss to 13th-seeded
It is Sharapova's earliest defeat at Roland Garros since 2010, when she was beaten in the third round. Since then, the Russian has won the clay-court Grand Slam tournament in 2012 and 2014, was the runner-up to
In another fourth-round match, Serena Williams looked curiously flat at times against
Stephens threw everything at Williams, literally. In the eighth game of the third set, she tossed her racket at a ball that fizzed past her forehand.
But it is Williams, not Stephens, who will be the only U.S. woman in the quarterfinals.
On the men's side, Roger Federer triumphed for the fourth time in four matches against Gael Monfils, winning 6-3, 4-6, 6-4, 6-1.
The 17-time Grand Slam champion next plays his Davis Cup Swiss teammate, Stan Wawrinka.
Andy Murray overcame a partisan crowd and Frenchman
The third-seeded Murray was whistled and booed several times in his 6-4, 3-6, 6-3, 6-2 win but stayed cool to set up a quarterfinal against
Against Sharapova, Safarova dictated much of the action and held her nerve as her far more experienced and accomplished foe tried to mount a comeback in the second set.
The left-handed Safarova wound up with a considerable edge in winners, 34-20, including forehands on the last two points to break Sharapova.
In her first French Open quarterfinal, Safarova will face No. 21 Garbine Muguruza of Spain, who beat No. 28