James scored 16 in the second half and the Cavaliers shot a season-best 61% from the field to improve to just 3-6 against
Cleveland, which has won eight of nine at home, is 9-2 when James has at least nine assists.
Marc Gasol scored 23 and added 11 rebounds for the Grizzlies, who played without forward
Jon Leuer added 16 points for Memphis, which dropped to 21-6.
Despite not having Randolph, their leading rebounder, the Grizzlies were still within 79-74 when the Cavaliers went on an 8-0 run to take control. Irving triggered the spurt with a basket before Waiters fed James for an alley-oop dunk. Waiters then drained a three-pointer to cap an 11-3 run, and the backup guard who has been inconsistent this season scored eight consecutive points to push Cleveland's lead to 100-83.
New Orleans 101, at Oklahoma City 99:
Phoenix 104, at Washington 92:
at Miami 100, Boston 84: Luol Deng scored 23 points,
at Brooklyn 110, Detroit 105:
at Toronto 118, New York 108:
Indiana 100, at Minnesota 96: