The Broncos, who will be playing in the Super Bowl for the seventh time, beat the New England Patriots, 26-16, in Colorado on Sunday.
The Seahawks, who will be making their second appearance in the Super Bowl, came back from a 10-0 deficit to beat the San Francisco 49ers, 23-17, in Washington state on Sunday.
The Broncos are considered to have the best offense in the league, while the Seahawks are regarded to have the best defense.
So who has the edge?
Vote in our poll on who you think will win and feel free to explain your reasoning with a comment.