In other matches, Spain's Carla Suarez Navarro upset fourth-seeded
The 25-year-old Suarez Navarro won the Portugal Open in May for her first WTA Tour title. She'll face Venus Williams in the quarterfinals. Williams beat
Makarova will play qualifier Coco Vandeweghe, a 7-6 (8), 2-6, 7-5 winner over seventh-seeded Jelena Jonkovic.
Djokovic came in with 11 straight wins over Tsonga but was nowhere near adding a 12th.
"Just nothing was going," Djokovic said. "No baseline, no serve, no return. So just generally very bad day, very poor performance."
Tsonga will play eighth-seeded
Djokovic's loss was the second big upset of the day. Third-seeded Stan Wawrinka lost, 7-6 (8), 7-5, to