The Penguins had scored first in each of their five games this season, but Cizikas gave the Islanders a well-earned early lead by stealing the puck from Paul Martin deep in Pittsburgh's zone then swooping behind the net and wrapping it around an outstretched Fleury.
The goal served as an exclamation point on a period the Islanders dominated in a place they rarely win. New York came in losers in 13 of its past 14 visits to Pittsburgh, the victory a 5-3 triumph last March that derailed any hopes the Penguins had of catching the New York Rangers for the Atlantic Division title.
Pittsburgh expects to be in the mix again during this truncated 48-game season but has hit an early rough patch that left the largest crowd in the brief history of Consol Energy Center voicing its displeasure following another disjointed effort.
The Penguins were drummed 5-2 by Toronto in the home opener last Wednesday and appeared no sharper six days later against a young, quick team that flustered Pittsburgh with its forechecking.
Not that the Penguins needed any help giving it away.