Nick Acuna ran 160 yards on 24 carries, leading a Bosco Tech (3-4, 1-1) ground game that gained 352 yards.
Randle Harris scored five first-half touchdowns and Encino Crespi's defense held Playa del Rey St. Bernard to eight first downs as the host Celts defeated the Vikings.
Harris rushed 18 times for 121 yards and four touchdowns and caught a nine-yard scoring pass from Kevin Vollmer.
The victory moves Crespi (6-1, 2-0) into first place, a half-game in front of defending league champion Gardena Serra, which plays tonight and will face the Celts next week.
St. Bernard (5-2, 1-1) scored first on an 80-yard pass play from Kennedy Offoegbu to Jared Billups, but Crespi answered by scoring on five of its seven first-half possessions. The two non-scoring possessions were turnovers in St. Bernard territory.
St. Bernard closed to within 22-13 after an 80-yard touchdown run by Marcus Crockett in the second quarter, but Harris had scoring runs of two and five yards before the half that gave Crespi a 36-13 lead.
St. Bernard held Crespi to 27 second-half yards and Harris had only 28 yards after intermission, but the Vikings were unable to capitalize. Trailing, 36-19, the Vikings saw an Offoegbu pass fall incomplete on fourth down from the Crespi six-yard line with 7:03 to play.
The Celts took over and gained four first downs to use up the rest of the clock.
DEL RIO LEAGUE
La Serna 31, Whittier 0
Ricky Beltran rushed for 142 yards on 14 carries and also had an interception for La Serna (7-0, 2-0). Ernie Cooper added 75 yards on seven carries with two touchdowns. Whittier is 4-3, 0-2.
Santa Fe 28, El Rancho 22
California 28, Pioneer 9
DESERT MOUNTAIN LEAGUE
Mammoth 35, Boron 7
DESERT SKY LEAGUE
Barstow 14, Victor Valley 0