Wiest will play Talia, the mother of formerly estranged sisters Sarah (Parker Posey) and Coco (Lauren Ambrose). The mismatched sisters become roommates when Coco agrees to carry Sarah's baby.
Other co-stars include Scott Cohen, Michael Arden and Ron McClarty.
In addition to her pair of Oscar wins for Woody Allen's "Bullets Over Broadway" and "Hannah and Her Sisters," Wiest won an Emmy for a guest appearance on "Road to Avonlea." D.A. Nora Lewin on "Law & Order," Wiest's other recent TV credits include the telefilms "The Blackwater Lightship" and "Category 6: Day of Destruction."