All southbound lanes of the 5 Freeway near Sheldon Street in the Sun Valley area were closed Monday night after a fatal collision, the California Highway Patrol said.
The lanes were expected to remain closed until around 10 p.m, the agency said. The incident was reported about 7:45 p.m.
Initial reports from officers at the scene stated that a body was lying in the middle of the freeway and may have been hit by more than one vehicle, the CHP said.
There were reports that the victim may have been a pedestrian, but that was not immediately clear, according to the agency's Los Angeles traffic management center.
Fire engines and at least one ambulance were trying to maneuver amid traffic on the busy freeway. No other details were immediately available.