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Keep The Webs Down With The Best Spider Killer

In many cases, spiders are beneficial insects that will help control other insect problems like flies, mosquitoes, roaches and other pests. But spiders can become pests too, especially black widows and brown recluse spiders that can give a painful bite when disturbed. When spiders become a problem, you'll need a good spider killing spray to deal with them. Although catch and release is the best way to deal with spiders, it isn't practical in all cases, so using a spider killer may be the best solution.

Every spider killer on the list of the best spider killers in 2021 will be effective, but the best one will be the safest to use, be readily biodegradable, made with natural ingredients and it will also be the best bang for the buck deal here. As always, wear a face mask and rubber gloves when using any of these products.

Here are the best spider killers of 2021

Southern Ag Pyrethrin Spider Killer - Best Spider Killer Overall

The safest to use, the best bang for the buck, and just as effective as anything else, that's what you get with Southern Ag Natural Pyrethrin Concentrate. First of all, it's a concentrate. You mix a cap-full or two into a quart spray bottle and then add water. 8 ounces of concentrate is going to equate to about 20 quarts of mix. That is an incredible value. It's made with natural pyrethrins, which is an insecticide made from the chrysanthemum plant. It's water soluble, biodegradable, and about as safe as a spider killing insecticide can be. Pyrethrin works to disrupt the neurological function in a spider, so death is relatively quick and painless. This is the best insecticidal spider killer there is, and it's so versatile that it can be used as a generic insect control substance. Great stuff.

Terro 2300 16-Ounce Spider Killer - Runner Up

From a name you know and trust, TERRO Spider Killer Spray will get the job done. It is made with two synthetic pyrethrin ingredients, which act as neurotoxins, so although not natural, it still breaks down and is relatively environmentally friendly. The carrier is a mineral oil based substance, so once sprayed, it offers a residual effect that keeps killing spiders for up to 12 weeks. It comes complete and ready to use in a can, spray it on webs or where spiders are lurking, and let the active ingredients do the rest.

Hot Shot Scorpion and Spider Killer - Honorable Mention

For the longest lasting residual effect in a spray, choose Hot Shot Spider and Scorpion Killer. It is made with a synthetic pyrethrin derivative, that is mixed with two types of carrier oil substances that keep the active ingredient working for up to 16 weeks. Although this is one of the more expensive spray type of spider killers, if you have a severe spider problem and want to keep them from coming back, this may be the best alternative for that. Spray it on webs, on known spider paths, in cracks and crevices for unrivaled residual protection that can't be beat.

Wet & Forget Miss Muffet's Revenge Spider Killer - Consider

This may be the best spider killing spray that you've never heard of. Spider Not Aerosol Kills Spiders, true, but it is also packaged in a highly pressurized spray can that will easily reach high up on ceiling or corners where most sprays won't go. It will actually kill any spiders as the blast from the can will knock down any webs if they are present. The active ingredient is a synthetic pyrethrin named D-Trans Allethrin. Although like most synthetic pyrethrins, it is relatively safe and not very toxic to humans, this particular formula is very toxic to cats. The petroleum distillate oils it is mixed with give it a very high residual effect, and although safe and effective in most situations, if you have cats as pets, use something else.

mdxconcepts Organic Home Pest Control Spray Spider Killer - Best Spider Killer

For the best deal in a spider killing spray, get Black Flag Spider and Scorpion Killer Aerosol Spray. Made of a synthetic pyrethrin in a mineral oil mix, this spray kills as well as anything else and lasts up to 16 weeks of residual effectiveness. If we were giving a bang for the buck award for a spray can, this one takes the prize. Realistically, every other spider killing spray kills spiders just as effectively, but Black Flag costs less then any of the other spray types on this list. It is cost effective to use, lasts long and you won't go broke if you need a couple of cans for a major spider infestation.

Buyer's Guide

Why Would You Need a Spider Killer?

Although they are quite self-explanatory, spider killers are highly effective in eliminating spiders from various corners inside your home. If you start noticing spider webs in every nook and cranny, they are a sign that you need to get your hands on a spider killer immediately. Usually, spiders make their way into homes in the months of September and October, so it is wise to buy a spider killer beforehand.

You may also consider hiring an exterminator instead of getting a spider killer, thinking that it may be a long-term option. However, unless you see dozens of spiders in your home, you won’t need to pay for an exterminator, which would cost a lot more than using a spider killer.

How to Use a Spider Killer?

No matter which spider killer you get, you can apply it in different ways throughout your house. Firstly, if there is a spot from where you notice the spiders entering your home, you can spray the solution around it, as well as all the entry points of your house. It is also wise to spray this solution from the outside as well.

Moreover, if you notice spiders in or around your furniture, then you can spray the spider killer all around it, including the baseboards, hinges, and joints. You can also spray this solution in the corners of every adjacent wall, so that you can get rid of them for good.

No matter what type of spider killer you are using, make sure to cover your face or wear a face mask, since it may contain chemicals that can be dangerous to inhale, thus being harmful for your health.

What Types of Spider Killers are There?

Spider killers come in different types, and they vary by the way they are applied. Some of the types of spider killers include:

AerosolsThis is one of the simplest and most effective types of spider killer. Aerosol solutions have a further reach and they can be sprayed from a distance. Also, they have a wider coverage and can eliminate spiders much faster than other methods.


Sprays are similar to aerosols, but they don’t come in a pressurized container. Therefore, they have a limited reach and coverage, so you will have to spray them from really close on the spiders. However, they are much safer to use, and can kill spiders much quicker.


Traps are another popular method for killing spiders and other insects. They consist of a glue that spiders stick to whenever they step over it. This is a more non-toxic and human-safe way of killing spiders. However, you should be careful, since they can be difficult to remove if stuck to human skin.


You can also find insecticide dusts, which are useful for killing spiders if you apply them close to their webs. They contain dust mites, which kill spiders as soon as they crawl over them. This type of spider killer can be used for indoor and outdoor purposes.

Ultrasonic Repellents

If you are looking for a much safer option for killing spiders, you can also consider buying ultrasonic repellents, which emit ultrasonic waves to drive pests and spiders away from your house. However, they don’t have an instantaneous effect like aerosols and sprays.

Things to Consider Before Buying a Spider Killer

There are various factors that you should keep in mind before choosing a spider killer to ward off these creatures from your home. Let’s go through all of these factors one by one.


Spider killers consist of certain ingredients and chemicals that work together to attack spiders and prevent them from laying eggs in every corner of your house. Most of these ingredients are highly effective, but they may also be detrimental for the health of humans and animals. Therefore, you should ensure that the spider killer you are getting contains substances that are safe for use inside the household.


Another factor to keep in mind when you are choosing the best spider killer is the area of application, i.e. whether you want to kill spiders outside or inside the home. Some spider killers are specially formulated for working outdoors, whereas others are more suited for indoor usage. On the other hand, you may also be able to find solutions that are effective in killing spiders both indoors and outdoors.


As mentioned earlier, most spider killers that kill spiders quickly can also be quite strong, meaning that they may have stronger ingredients that can be harmful for your health. Therefore, you can either choose non-toxic or safe spider killers, or you can take necessary precautions to ensure that the spray or dust doesn’t get into your eyes or nose.


The expiry date of spider killers is also an important factor to keep in mind, as you wouldn’t want to buy a product that would become useless or less effective in just a few months. You won’t be using all of the spider killer at once, so it will be lying around for a long time. So, make sure that the spider killer you choose has a longer shelf life, so that it works well whenever you need to use it.


You might also fall prey to the myth that more expensive products are more effective than less costly ones, but that is certainly not the case with spider killers. Once you check out the ingredients and area of usage for whichever product you come across, you can easily find a more budget-friendly option, so that you can quickly rid your home of all spiders.


Q: What are natural spider killers?
A: Natural spider killers are solutions that have natural and non-toxic ingredients, which are safe for the household and don’t cause any harm to you or your family members.

Q: What is the best time to use spider killers?
A: Ideally, you should spray or treat your home with spider killers as early as the start of spring season, because this is the time when spiders start nesting and laying eggs outside your home.

Q: Where should I apply the spider killer?
A: For indoor application, you can apply the spider killer wherever you see a spider or its web. Otherwise, you can apply the solution in the corners of your house, especially near the doors, windows, and other entry points.

Bestcovery Staff
Our research team searches out the best of everything so that you can confidently pick the perfect products and services for your needs.
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