Here are a few of our favorite quotes and insights from their interview:
On family and comedy: "The first thing that I learned — and I understood it at a really young age — was that I could get a laugh. Really early. Because my mother and father are funny. My father's a really funny man, and at the time we were growing up, in the mid-sixties, and I was like 7 years old, they always had dinner parties. ... And my dad would tell, you know, a story, something a little risqué — nothing dirty at all, just a little risqué. And I knew that I could take the next step, right? The little-bit-dirtier version. You know — 'and deep, too!' And the place would explode! And Dad would kick me under the table — but I always knew that I had that in my arsenal."
On being a star: Since Clooney's career catapulted at a relatively later age, he likes to say he "came from somewhere" and "can still fix a fan belt" on a car.
"I had my Aunt Rosie, who was famous and then not, so I got a lesson in fame early on. And I understood how little it has to do with you. And also how you could use it."
"But then I had a year. Then I had 'Syriana' and 'Good Night, and Good Luck,' and he was gonna see me at the
A bit of insight from the $15-million Obama reelection fundraiser that took place at his Los Angeles home in 2012: "The president came here and there were some people who wanted to meet him. And the president and I are talking to them and they're holding their smartphone cameras up like this. And I'm holding my hand out trying to shake their hand, and they're like, 'Smile.' And I said to the president, I said, 'You know, the oddest thing about what's happening right now is that we've stopped living our lives and we're just recording them.'" (He also likes to hand-write his scripts and doesn't allow cellphones at dinner)
On his big dislike/disapproval of celebrities on Twitter: "If you're famous, I don't — for the life of me — I don't understand why any famous person would ever be on Twitter. Why on God's green earth would you be on Twitter? Because first of all, the worst thing you can do is make yourself more available, right? Because you're going to be available to everybody. But also Twitter. So one drunken night, you come home and you've had two too many drinks and you're watching TV and somebody pisses you off, and you go 'Ehhhhh' and fight back.
On "ER," which kick-started his career at age 33:
"It was a hard, hard job, 'ER.' We were working 16-hour days, five days a week. We were learning Latin, you know, to do the show. But you knew that you were never going to get a second chance to introduce yourself to a wide audience. And I was 33. I wasn't the young one there; I was the oldest one there. So I knew this was my opportunity. I think all the actors were given a bit of an opportunity that summer on a film. I think every one of them was given an opportunity. And I think most of them were so exhausted from the work that they wanted their summer off.
"In fairness, they were also doing a lot. I had the smallest part in the show. And when [Robert Rodriguez's] 'Dusk Till Dawn' came around . . . well, it was a great part for me, because it was a complete departure. And that movie changed everything for me ... ."
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