In Springfield: Homer gets a medical marijuana prescription, Matt Groening becomes the second "Simpsons" creator to appear as himself on the show (after Conan O'Brien). Beyond Springfield: September 11 attacks, Enron files for bankruptcy, U.S. invades Afghanistan. Notable guests: Robert Pinsky, Stan Lee, Phish, R.E.M., Paul Newman, Reese Witherspoon. Season rating: 12.4 million.
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