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Caltech researchers help 'bridge the gap' for HIV antibodies
Caltech researchers help 'bridge the gap' for HIV antibodies

Anybody who's ever hung from the bars of a playground jungle gym knows it's easier to latch on with two arms instead of one.  The same might be said of immune system antibodies: The "Y" shaped proteins do a better job of clinging to invader viruses when they use both of their arms, or binding sites, instead of just one. In research published Thursday in the journal Cell, scientists at Caltech described how the structure of HIV often prevents antibodies from using both arms. They also offer a genetically engineered solution to the problem. In fact, reasearchers say their altered antibodies are, on average, more than a 100 times better at neutralizing HIV than...

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