A good friend and I had a delightful week in Rome at the end of September. We stayed at the lovely Daphne Inn, a boutique hotel near the Piazza Barberini. Rates were reasonable for such elegant and friendly digs, about $270 per night. Up the street is an excellent restaurant and wine bar called Moma, with wonderful food, charming service and fair prices. I highly recommend both.
Daphne Inn, 55 Via di San Basilio, Rome; 011-39-6-874500867, http://www.daphne-rome.com