Schumer penned the script for the comedy, the plot of which has yet to be revealed. Release is scheduled for July 24, 2015.
"I know you're very busy with the playoffs," Apatow says in the video. "But I just wanted to say we're so glad that you are joining the cast … and now the world will finally get to see what your true gifts are."
James, a four-time NBA most valuable player, has his hands full trying to lead the Miami Heat to its third consecutive championship, but he also represents a walking, talking, dunking brand name recognized around the world, a fact not lost on Hollywood.
"Trainwreck" marks Universal's third James-related venture: He is attached to star alongside