Medical Research

‘Bad luck’ with random DNA errors is responsible for two-thirds of cancer mutations, study says

‘Bad luck’ with random DNA errors is responsible for two-thirds of cancer mutations, study says

Even in a world with a pristine environment, no cigarettes and the ability to fix faulty genes inherited from our parents, most of the cancers diagnosed today still would occur thanks to a combination of biology and bad luck.

Every new case of cancer depends on a collection of specific mutations in our DNA, and a sweeping new study finds that 66% of the mutations that put us at risk for cancer are the result of unavoidable errors made by cells as they copy themselves millions of times throughout our lives.

In research published Thursday in the journal Science, geneticist Bert Vogelstein...

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