The Luc Besson movie is the latest success for Johansson in China, where she's built a following through appearances in "Iron Man 2," "The Avengers" and this year's "Captain America: The Winter Soldier."
"Guardians of the Galaxy" added $17.7 million to its haul last week, pushing its cumulative take in the territory to almost $86 million.
In third place for the week was Ning Hao's blockbuster road comedy, "Breakup Buddies," which took in an additional $10.8 million and has now grossed nearly $185 million, one of the best performances ever for a Chinese film.
In fifth place for the week was the local production "Dearest," a child-abduction drama that has taken in more than $55 million.
China's total box office take for 2014 now stands just shy of $4 billion with more than two months left to go in the year.