The Clippers, who led by as many as 19 points, outshot the Wizards, 52.3% to 43%, outrebounded them, 46-36, and made twice as many three-pointers -- 12 to the Wizards' six.
Chris Paul led the Clippers with 30 points and 15 assists. J.J. Redick had 26 points on nine-for-15 shooting, making four three-pointers. And Blake Griffin, in his fourth game back after missing 15 games because of a staph infection in his right elbow that required surgery, had 22 points, six rebounds and five assists.
The Clippers have won three of their four games since Griffin returned.
Matt Barnes, who started Friday after missing the last two games because of soreness in his right hamstring, struggled a bit, scoring eight points on three-for-10 shooting in 30 minutes. Jordan Hamilton, signed Friday for the remainder of the season, didn't play as he recovers from a sprained right ankle.
It was Jamal Crawford's birthday Friday, but the reigning sixth man of the year missed his ninth game because of a bruised right calf.
The Clippers (45-25) are in fifth place in the Western Conference, only half a game behind the fourth-place Portland Trail Blazers, two games behind the third-place Houston Rockets and 3 1/2 games behind the second-place Memphis Grizzlies. The Clippers were in seventh place in the competitive conference earlier this week.
The Wizards (40-29) are in fifth place in the East.
The Clippers host the New Orleans Pelicans on Sunday before leaving on a three-game trip.