Baker Mayfield threw for 487 yards and four touchdowns and ran for another 85 yards and two scores to power No. 16 Oklahoma over Tulsa, 52-38, on Saturday in a game that totaled nearly 1,400 yards of offense.
Mayfield set a school record with 572 total yards. He got plenty of help in a game that featured touchdowns galore. Samaje Perine ran for 152 yards, Sterling Shepard caught eight passes for 144 yards and Mark Andrews caught two TD passes for the Sooners (3-0).
Tulsa (2-1) stuck with the Sooners for much of the game with Dane Evans throwing for 427 yards and four touchdowns and Keyarris Garrett catching 14 passes for 189 yards.
Oklahoma led 31-24 at halftime. The teams combined for 863 yards in the first half, the most in a first half since Fresno State at San Jose State combined for 1002 in a 2013 game.
Tulsa and Oklahoma combined for 1,376 yards.
No. 15 Mississippi knocks off No. 2 Alabama, 43-37
Chad Kelly completed a deflected 66-yard touchdown pass and added two more long ones in the fourth quarter to help Ole Miss win in Tuscaloosa, Ala.
The Rebels (3-0, 1-0 Southeastern Conference) left the topsy-turvy game with their first victory in Bryant-Denny Stadium since 1988, and second straight in a one-sided series. The Crimson Tide (2-1, 0-1) had been 25-1 in Tuscaloosa against Ole Miss and had never lost two straight.
The Rebels made two final defensive stands, the first when Tony Bridges intercepted a deep ball from Jake Coker, who came off the bench to lead a comeback from a 30-10 deficit.
Kelly delivered big play after big play after an ineffective first half, none wilder than a fling and a prayer in the third quarter, a 66-yard deflection caught by Quincy Adeboyejo for a touchdown.
Stanford upsets No. 6 USC, 41-31
Kevin Hogan passed for 279 yards and two touchdowns, Remound Wright rushed for three more scores and Stanford opened Pac-12 play with a victory at the Coliseum.
Austin Hooper and Devon Cajuste caught touchdown passes as Hogan finally beat USC for the first time in his career, snapping the Trojans' two-game winning streak in the lively in-state rivalry.
Christian McCaffrey rushed for 115 yards for the Cardinal (2-1, 1-0), who scored just six points in their stunning season-opening loss at Northwestern. They looked more like their usual powerhouse selves Saturday during a 474-yard offensive performance at the Coliseum, where they've won four times in their last five trips.
Cody Kessler was 25 of 32 for 272 yards and three touchdowns, but USC (2-1, 0-1) couldn't match the steady production of Hogan, who went 18 for 23, and his dominant offensive line.
Steven Mitchell Jr. caught two touchdown passes and JuJu Smith-Schuster caught another, but preseason Pac-12 favorite USC failed its first test of the season after beating two Sun Belt opponents by a combined 99 points earlier this month.
No. 1 Ohio State escapes with 20-13 win over Northern Illinois
Darron Lee returned an interception 41 yards for a touchdown and top-ranked Ohio State's defense bailed out its struggling, two-quarterback offense.
Cardale Jones started for the Buckeyes (3-0) and J.T. Barrett finished, but for the second straight week neither was particularly effective against an opponent Ohio State was expected to blow out.
Jones threw two interceptions and went to the bench in the second quarter. Barrett threw a touchdown pass and an interception. Ohio State had five turnovers in all, but still managed to extend the nation's longest winning streak to 16 games.
Last week, the Buckeyes shook free of Hawaii in the second half, but they couldn't do the same with Northern Illinois (2-1).
The Huskies cut the lead to 20-13 on a field goal with 7:46 left in the fourth quarter, and got the ball back when Marlon Moore forced a fumble by Curtis Samuel and Northern Illinois recovered at its own 25 with 4:05 left in the game. The Buckeyes clamped down again with Joey Bosa and Sam Hubbard crunching Drew Hare for a sack on third-and-long. In need of one first down to wrap it up, Ohio State came up short.
Northern Illinois' last drive started at its 20 with 1:34 left, but Hare threw four incomplete passes under duress and Ohio State could finally take a knee.
No. 3 TCU tipples SMU, 56-37
Trevone Boykin threw for 454 yards and five touchdowns for TCU and added a highlight scoring run when he ducked out of a sack.
The Horned Frogs (3-0) won their 11th consecutive game, a winning streak second only to the 16 in a row by top-ranked defending national champion Ohio State.
TCU was up 42-17 when Boykin threw a 31-yard TD pass to Kolby Listenbee on the first series after halftime. But SMU, with its own dual-threat quarterback in Matt Davis, scored the next 20 points before Boykin's 42-yard scoring strike to Josh Doctson with 6:32 left.
Boykin, who finished fourth in the Heisman Trophy voting last year, completed 21 of 30 passes. His only interception did help the late surge by SMU (1-2), but the senior quarterback made another big throw to Doctson to make sure the Frogs avoided being upset in the Battle for the Iron Skillet.
Doctson had five catches for 171 yards and two touchdowns. Aaron Green ran 21 times for 164 yards with two scores, including a 1-yarder in the final minute.
Aaron Burbridge leads No. 4 Michigan State past Air Force, 35-21
Connor Cook threw three touchdown passes in the first half — including one hauled in by Aaron Burbridge with a spectacular catch in the end zone — and No. 4 Michigan State beat Air Force, 35-21, on Saturday.
Cook ended up throwing for 247 yards and four touchdowns, and Burbridge caught eight passes for 156 yards and three TDs. The highlight was Burbridge's 28-yard scoring reception in the second quarter, when he leaped to make the catch and, as his body stretched parallel to the ground, touched his left foot down in bounds.
The Spartans (3-0) were coming off a big win over Oregon, and Air Force's option isn't easy to prepare for, but the Falcons (2-1) never mounted much of an upset threat.
No. 7 Georgia easily handles South Carolina, 52-20
Greyson Lambert answered his skeptics with a near-perfect performance, throwing for 330 yards, three touchdowns and setting a Georgia record with 20 straight completions.
Nick Chubb eclipsed 100 yards rushing for the 11th game in a row, carrying 21 times for 159 yards and two scores. Sony Michel ran for a TD and had two more receiving.
Georgia (3-0, 2-0 Southeastern Conference) seized control with a touchdown in the final seconds of the first half and two more in the first 2 1-2 minutes of the third quarter, taking advantage of an interception by South Carolina's new starting quarterback, former walk-on Perry Orth.
South Carolina (1-2, 0-2) has lost its first two SEC games for the first time since 2008. It was the most points a Steve-Spurrier coached team has ever given up to Georgia.
No. 8 Notre Dame holds off Georgia Tech, 30-22
C.J. Prosise ran for 198 yards and three touchdowns, including one for 91 yards, and Notre Dame shut down Georgia Tech's high-powered offense.
Patrick Skov scored on a 24-yard run and a 15-yard catch in the final minute after the Yellow Jackets recovered an onside kick, but Notre Dame's Torii Hunter Jr. recovered a second onside kick with 21 seconds left to clinch the victory.
Georgia Tech (2-1) entered the game averaging 67 points and 457 yards rushing, but struggled to get much going until the final minute. The Fighting Irish held the Yellow Jackets to 216 yards rushing.
Notre Dame is 3-0 for the third time in the past four seasons.
No. 12 Oregon routs Georgia State, 61-28
Jeff Lockie threw for 228 yards and two touchdowns in his first start for Oregon.
Lockie replaced Vernon Adams, who was rested with a broken index finger on his throwing hand.
Royce Freeman ran for 101 yards and a touchdown to help the Ducks (2-1) rebound from a loss at Michigan State. Aidan Schneider added four field goals, all in the first half as Oregon built a 33-7 lead.
Nick Arbuckle threw for 318 yards and three touchdowns, and freshman Penny Hart had nine catches for 128 yards for the Panthers (1-2).
No. 13 LSU romps past No. 18 Auburn, 45-21
Leonard Fournette ran for a career-high 228 yards and three touchdowns, and LSU steamrolled Auburn.
Fournette gained 71 yards on LSU's first play from scrimmage and had 169 yards by halftime, then was rested for much of the second half — perhaps the only thing preventing him from breaking Alley Broussard's single-game LSU rushing record of 250 yards, set against Mississippi in 2004.
LSU (2-0, 2-0 Southeastern Conference), finished with 411 yards on the ground. Quarterback Brandon Harris added 66 yards and two touchdowns.
Auburn (2-1, 0-1), which needed overtime to avoid an upset by Jacksonville State a week earlier, trailed 24-0 at halftime and never threatened thereafter.
No. 17 Texas A&M rumbles past Nevada, 44-27
Kyle Allen threw four touchdown passes and ran for another as No. 17 Texas A&M and pulled away for a 44-27 win over Nevada on Saturday.
It was the 19th straight non-conference victory for the Aggies, the longest active streak in the Football Bowl Subdivision.
The Aggies were up by four early in the second quarter before scoring 17 straight points, with two touchdown catches by Josh Reynolds, to make it 31-10 early in the third. The second one came soon after an interception by Donovan Wilson on the first play of the second half.
Though Texas A&M (3-0) came away with a decisive win, coach Kevin Sumlin will undoubtedly be unhappy with his team's two turnovers with the SEC opener against Arkansas coming up next.
Tyler Stewart threw for 206 yards with two touchdowns and an interception for Nevada (1-2).
No. 22 Missouri holds off Connecticut, 9-6
A last-minute interception by safety Anthony Sherrils allowed No. 22 Missouri to hold on for a 9-6 victory over Connecticut in a game that featured four turnovers, two missed field goals and a blocked extra point.
With just a under a minute left, Sherrils picked off a pass by Huskies backup quarterback Tim Boyle on a fourth-down, fake field goal attempt to seal the win.
Sherils also forced and recovered a fumble with 4:26 left in the first half for Missouri (3-0). UConn is 2-1.
Missouri took a 2-0 lead in first-quarter on a safety after Clarence Greene blocked a punt that went out of the end zone. After UConn scored a touchdown to take the lead later in the period, linebacker Kentrell Brothers blocked the extra point.
Maty Mauk completed 14 of 22 passes for 145 yards and an interception. His 2-yard touchdown run near the end of the third quarter gave the Tigers the lead for good.
Ish Witter made his first career start for Missouri in place of the injured Russell Hansbrough, and carried the 17 times for 54 yards.
No. 23 Northwestern stays perfect, beats Duke, 19-10
Warren Long ran 55 yards for a touchdown and recovered a fumbled punt return late to help No. 23 Northwestern beat Duke 19-10 on Saturday.
Solomon Vault returned the opening kickoff of the second half 98 yards for the touchdown that put the Wildcats (3-0) ahead to stay.
Northwestern forced three turnovers and opened a season with three victories for the first time since 2013 — also the last time the Wildcats were ranked.
Thomas Sirk had a 5-yard touchdown run for Duke (2-1), which trailed 12-10 early in the fourth quarter but forced Northwestern into a third-and-1 at its own 45.
Long took a handoff, burst untouched through the line and sprinted to the end zone to put the Wildcats up by nine with 12:31 remaining.
No. 24 Wisconsin takes care of Troy, 28-3
Two-way player Tanner McEvoy had one of Wisconsin's three touchdown runs in a game where two Badgers defenders were ejected for targeting and play was delayed briefly in the fourth quarter because of an errant fire alarm.
Dare Ogunbowale and quarterback Joel Stave also ran for scores for Wisconsin (2-1).
Starting inside linebacker Leon Jacobs was thrown out in the first quarter, and cornerback Derrick Tindal was ejected in the third. The fire alarm led to a delay with 8:56 left and Troy (1-2) driving.
No. 25 Oklahoma State routs Texas San Antonio, 69-14
Devante Averette scored on a 6-yard fumble return only 45 seconds in, and Oklahoma State forced seven turnovers — all of them leading to points.
Mason Rudolph completed 17 of 23 passes for 280 yards and two touchdowns, and Chris Carson rushed for 104 yards and two touchdowns on 17 carries for Oklahoma State (3-0).
Blake Bogenschutz was 8 of 13 for 58 yards and a touchdown for UTSA (0-3), but also fumbled twice and threw two interceptions before he was taken out of the game late in the second quarter.
Wake Forest beats Army, 17-14, with last-second field goal
Freshman quarterback Kendall Hinton scored two touchdowns in the second half, Mike Weaver kicked a 47-yard field goal as time expired, and Wake Forest rallied past Army, 17-14, on Saturday.
Wake Forest (2-1) overcame three interceptions to win its ninth straight in the series with Army (0-3). Last year, Wake Forest rallied for a late touchdown and then forced an Army fumble in a 24-21 victory at home.
Pressed into action when starter John Wolford went down with an ankle injury in the first quarter, Hinton overcame two interceptions, scoring on runs of 15 and seven yards after the Army defense pitched a shutout in the opening half.
Hinton, who finished 15 of 27 for 159 yards, also torched the Black Knights with a pair of clutch long throws. His 51-yard completion to KJ Brent set up Hinton's tying touchdown, and his 28-yarder to Cortez Lewis set up Hinton's second score.
Syracuse beats Central Michigan, 30-27, in OT
Jordan Fredericks rushed for 73 yards on 11 carries, including the game winning 4-yard touchdown run in overtime, to help Syracuse escape with a 30-27 victory over Central Michigan on Saturday.
Syracuse led almost the entire way and held a 24-10 lead at halftime. But the Chippewas battled back late to force overtime on a Cooper Rush 27-yard touchdown pass to Ben McCord with seven seconds remaining in regulation, capping off a 12-play, 90 yard drive that took just 2:10.
Brian Eavey kicked a 20-yard field goal for Central Michigan on its first overtime possession after Syracuse held on 3rd and goal at the one yard line.
Three quarterbacks combined for 161 passing yards and two touchdowns for the Orange, with Eric Dungy leading the way with 93.