The Wildcats had their way inside and out in one of their best offensive performances of the season, shooting 59% while outscoring the Ducks, 44-18, in the paint.
"That was one of our best games all year," Arizona point guard T.J. McConnell said.
It was Arizona's 33rd straight victory at home.
Elgin Cook had 16 points and Joseph Young added 12 for Oregon.
at Arizona State 73, Oregon State 55: Shaquielle McKissic scored 17 and the Sun Devils made eight first-half three-pointers. The Beavers came into the game with the Pac-12's top-ranked three-point defense. Arizona State led by as many as 22 points in winning its third game in the last four.
Stanford 84, at Washington 74: Anthony Brown scored 23 points and the Cardinal took advantage as the Huskies played their first game since dismissing center Robert Upshaw for unspecified rule violations. That left little inside resistance for Cardinal center Stefan Nastic, who scored 15 in the first half and 17 total.