The Lakers lost their eighth consecutive game, falling on Friday night to the Memphis Grizzlies at Staples Center, 112-95.
Kobe Bryant was a late scratch, sitting to rest a sore shoulder. Rookie Anthony Brown started in his place, scoring five points in 32 minutes.
Without their veteran All-Star, the Lakers were flat against the Grizzlies, most visibly on the defensive end.
The Lakers gave up 67 first-half points to the Grizzlies -- a team that averages 98.6 points a game and is without Marc Gasol for the rest of the season.
In the Lakers' loss Wednesday in Memphis, they gave up at least 30 points in every quarter. That streak extended to six Friday, until the third period, when the Grizzlies scored only 23.
Vince Carter gave his team early separation from the Lakers, making his first five three-point attempts. He finished the game with 19 points
P.J. Hairston scored 21, while Mike Conley added 17, Zach Randolph 15 (with 10 rebounds and five assists), Lance Stephenson 14 and JaMychal Green 10.
The Grizzlies shot 50.6% from the field, 40.6% from three-point range (13-32) and 86.7% from the line (13-15).
The Lakers made 41.0%, 21.7% (5-23) and 66.7% (26-39), respectively.
D'Angelo Russell was the game's leading scorer with 22, getting to the line 12 times for eight points. Julius Randle scored 17 and Lou Williams 13.
The Grizzlies led by as many as 29 points.
The Lakers (11-49) are off until Tuesday, when they will host the Brooklyn Nets (15-42). The Grizzlies (34-23) next visit the Phoenix Suns (14-44) on Saturday.