The Lakers limped through Week 24, dropping three more games to see their losing streak grow to seven.
Kent Bazemore was also declared out for the remainder of season with a torn foot tendon.
Nash noted that the down year wasn't D'Antoni's fault and that not even John Wooden would have been able to help the Lakers.
Jordan Farmar returned from a groin injury, and while D'Antoni was happy to have Farmar and Nash back, Nash's nerve root issue may keep him out the rest of the season.
The Lakers may be able to climb in the NBA draft lottery from sixth to as high as fourth, with the Boston Celtics on a two-game winning streak and the Utah Jazz just one win "ahead" of the Lakers. Of course the actual lottery itself could jump the Lakers to a top-three pick -- or drop the franchise as low as three spaces to nine.
Connecticut senior Shabazz Napier made his draft case, winning his second NCAA title with a win over Kentucky.
Before the game, former Wildcat Rex Chapman tweeted that Coach John Calipari is a "done deal" to the Lakers after this season. The Lakers quickly denied that, and Chapman later followed up with a radio interview, saying he expects Calipari to be at Kentucky next season.
To help sort out these issues, the Lakers gave General Manager Mitch Kupchak a multiyear contract extension.
One big question ahead is the status of impending free agent Pau Gasol, who hasn't shut door on returning to the Lakers next season.
It's a crucial time for the Lakers, who have occasionally struggled to sell out at Staples Center this season.