The Raptors have already clinched a playoff berth in the Eastern Conference, but are hoping to climb from the fourth seed -- while holding off the fifth-place Washington Wizards (40-32).
Toronto has struggled of late, with Kyle Lowry sidelined with a back injury. The All-Star guard is questionable on Friday.
If Lowry does return to action, he's averaging 17.4 points and 6.9 assists a game, driving the Raptors' offense.
Without him, the Lakers will have to deal with a solid substitute in Greivis Vasquez, who scored 22 on Wednesday in a loss to the Chicago Bulls. Reserve Guard Lou Williams is another explosive scorer.
DeMar DeRozan is leading the Raptors in scoring at 19.4 points a game.
The USC product is more of a scorer than a true shooter, hitting 40.2% from the field and just 26.5% from three-point range.
The Lakers are probably best served with Wesley Johnson guarding DeRozan, although Ellington, Brown and Clarkson may all get a crack defensively.
The Raptors have a lot to play for, and while the Lakers have been competitive of late, Toronto should be able to protect their home court on Friday.