University of Oxford
Immunity, signaling genes may be linked to schizophrenia

The secret to schizophrenia, psychiatry’s most abiding mystery, may lie in the DNA associated with the body’s immune system, according to a genome-wide study published online Tuesday. The analysis of variations in nearly 150,000 DNA samples identified 108 regions that strongly correlate with the highly heritable disorder, which is marked by psychotic episodes and cognitive deficits. Many of the areas of DNA identified by the study either include a functioning gene or are close to one, including those previously associated with schizophrenia and other psychiatric disorders, according to the study published online Tuesday in the journal Nature. Though far from producing a...