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Genetically modified cells learn to fight mesothelioma

Genetically modified cells learn to fight mesothelioma

It’s been called the “fifth pillar” of cancer treatment: genetically reengineering the human immune system to recognize cancers and fight them.

The treatment has shown recent promise in fighting blood cancers such as leukemia. But hard tumors, such as mesothelioma, have proven to be more resistant to attack from these tinkered T cells when they were reinjected into the bloodstream.

Researchers at Memorial Sloan Kettering Cancer Center in New York tried delivering the modified white blood cells directly to the tumor area, and found that they not only eliminated the cancer, but proliferated and persisted, successfully fighting off a reintroduced cancer. Their...