McDonald has withdrawn from the production through July 3, citing inflammation of her vocal cords that resulted from an earlier respiratory infection. The actress' understudy, Alicia Hall Moran, will perform the role of Bess in her place. Moran already plays Bess in Wednesday evening performances.
McDonald is expected to return to the musical on July 3.
The production is a revised version of the Gershwin classic, with changes by playwright Suzan Lori-Parks and Diedre L. Murray. The show also won the Tony for revival of a musical.