Two people were shot Thursday night on the westbound 91 Freeway near Bellflower Boulevard, the California Highway Patrol said.
The shooting was reported about 8:45 p.m, the CHP said. Patrol units were responding.
It was not immediately clear what sparked the violence or how the shooting transpired.
Two victims were taken to a hospital, according to the Los Angeles County Fire Department.
The CHP said officers were looking for two male suspects.
All westbound lanes except the car-pool lane were closed on the 91 Freeway.
Television news footage showed vehicles that appeared to be involved in a crash near the shooting scene.