Thousands are expected to congregate at Grand Park in downtown Los Angeles on Saturday for an event headlined by Catholic Archbishop Jose Gomez.
The event, named OneLife LA, will celebrate "the beauty of every human life from conception to natural death" and feature speakers discussing adoption, human trafficking and suicide, among other topics, according to the Los Angeles Archdiocese.
"In the Christian vision, every human life is precious — created by God with transcendent dignity and endowed with rights that no one can deny or take away," Gomez said in a statement.
"OneLife LA will celebrate this vision and call us to action — to love life, to care for life and to protect life at every stage and every condition, beginning with the most vulnerable in the womb."
The event was expected to begin about 10 a.m. at La Placita Olvera, with participants marching to Grand Park in front of City Hall for a special ceremony, a release said.
Actress Patricia Heaton was among those expected to serve as presenters at the event, with Mexican singer Miriam Solis and "The Voice'' finalist Paulina Cerrilla performing. Some surrounding streets were temporarily closed to traffic.