Patrice O'Neal, 41, a veteran stand-up comic who gained a wider following through TV and radio and helped roast
in September, died Tuesday from complications of
he suffered last month. O'Neal's manager, Jonathan Brandstein, said he died at a New York-area hospital.
O'Neal grew up in Boston and started his stand-up career there. He appeared on
's late-night TV shows and was a frequent guest on the "Opie & Anthony" radio show on Sirius XM.
His performance was a highlight of the
roast of Sheen, who had been fired from the hit
O'Neal had half-hour specials on
and was the host of "Web Junk 20" on
. He also acted in the TV series
O'Neal, who was 6 feet 5, weighed about 300 pounds and had
, suffered a stroke Oct. 19.