Los Angeles has won seven of its last eight games, including a 105-85 win over the San Antonio Spurs on Saturday.
They went from being sixth in the Western Conference last week to third, only 5.5 games behind the first-place Golden State Warriors.
The Nets, who are in ninth place in the Eastern Conference, have lost four games in a row, and each of their last seven home games.
When the teams played in Los Angeles on Jan. 22, the Clippers won, 123-84. In that game, the Cilppers outshot the Nets from the field, 59% to 38%, and from beyond the three-point line, 44% to 19%.
The Clippers, however, have had less luck on the road against Brooklyn. L.A. has lost six in a row and 14 of their last 15 during away games in the series.