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Johns Hopkins University
A bacterium that destroys tumors' dark heart shows promise
A bacterium that destroys tumors' dark heart shows promise

A mutant form of a bacterium that lives in soil and thrives in low-oxygen environments appears to be a precise and aggressive killer of malignant tumors as well as an energetic activator of the body's immune system, according to new research. When scientists injected spores of a weakened form of the bacterium Clostridium novyi directly into the soft-tissue tumors of dogs and that of a single human subject, the results were not only abscesses, fever and pain at the site--all inflammatory responses that showed the immune system had been drawn to the area. In a matter of hours, the bacterial spores quickly found their way into these tumors' necrotic cores and began replicating...

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