Debra Messing and Will Chase split up after sparking during ‘Smash’

“Will & Debra” has come to an end: Debra Messing and Will Chase have split up.

The “Will & Grace” alum’s breakup news was confirmed to the Los Angeles Times on Monday.

“Debra Messing and Will Chase have ended their two and a half year relationship, but remain close friends,” her rep’s office said in a statement.

Messing, 46, and Chase, 44, were first linked in late 2011 when they were costarring in NBC’s now-canceled musical drama “Smash,” according to Us Weekly, which first reported the split.

Though she’s no longer starring in Chase’s life, the TV actress has a new NBC series to headline: “The Mysteries of Laura.”

Chase, a Tony Award nominee, has played Luke Wheeler on ABC’s country-music drama “Nashville” since 2013.

Messing was previously married to writer-producer Daniel Zelman, with whom she shares a son, Roman Walker Zelman, 10. She and Zelman were married from 2001 to 2011.

Chase was married to actress Stephanie Gibson from 2009 to 2012.

“Smashville” crossover, anyone? Follow me on Twitter @NardineSaad.