In Thursday's loss, the Clippers trailed by as many as 32 points, and they sent the Cavaliers to the free-throw line 44 times while only shooting 20 foul shots themselves.
The Clippers have lost two consecutive games, falling to the Brooklyn Nets, 102-100, before losing to Cleveland.
The Raptors, who have also lost two games in a row, have gone 9-9 since they held the top record in the Eastern Conference on Dec. 30.
The Clippers are in fifth place in the Western Conference with a record of 33-17. The Raptors are in second place in the Eastern Conference with a record of 33-17.
The last time the teams played, the Raptors won, 110-98. In that game, the Clippers committed 15 turnovers. The Raptors have not swept the season series from the Clippers since 2009-10.
The Clippers are 9-3 in the second leg of back-to-back games.