Orlando has lost 10 consecutive games, firing their head coach, Jacque Vaughn, on Thursday and installing James Borrego in the interim.
Meanwhile, the Lakers have struggled in their own right, losing 11 of their last 12.
Rookie forward Aaron Gordon (foot) is questionable for the Magic.
The Magic have one of the better young centers in the league in Nikola Vucevic, who is averaging 19.6 points and 11.3 rebounds a game.
Davis collected a career-high 20 rebounds on Wednesday in a loss to the Milwaukee Bucks.
Offensively, Carlos Boozer is the team's most reliable scorer at a power position, coming off a 28-point effort against Milwaukee.
Rookie Elfrid Payton has begun to blossom as the team's point guard, averaging 7.8 points and 5.8 assists.
The Lakers start rookie Jordan Clarkson at the point with mixed results. The Lakers need a strong performance from Jeremy Lin behind Clarkson. Wesley Johnson may be the best choice against Oladipo, although Wayne Ellington will likely get the first crack.
Perhaps the coaching change will inspire the Magic, but the Lakers have a real shot to win a game they shouldn't.