Pau Gasol added 18 points and 10 rebounds. Tony Snell scored 22, helping offset a 31-point performance by LeBron James, and the Bulls won their fourth straight after dropping 10 of 15. They entered the All-Star break with a 1 1/2-game lead in the Central Division over the Cavaliers.
Chicago led most of the way against the NBA's hottest team and pulled away in the fourth quarter.
Gasol posted his 14th straight double-double.