The singer and actress, 46, opened "Jennifer Lopez: All I Have" at Axis at Planet Hollywood Resort & Casino.
The show featured "10 costume changes, hoverboards, show-stopping choreography and a slew of famous faces ...," according to People magazine. Those who joined her on stage -- Ja Rule, Ne-Yo and Pitbull -- sang along at the sold-out performance.
Lopez delivers on her hit songs along with a five-piece band and 16 dancers as well as special effects and videos.
Tickets on sale at Planet Hollywood cost $59 to $229.
Dion canceled her concerts last weekend after the death of her husband, René Angélil, Jan. 14. She is expected to resume the show Feb. 23.