Kyle Kempt passed for 343 yards and three touchdowns, including a 25-yarder to Allen Lazard that put Iowa State ahead with 2:19 left, and Joel Lanning made plays on offense and defense to lead the Cyclones to a stunning 38-31 victory over No. 3 Oklahoma on Saturday in Norman, Okla.
The loss snapped Oklahoma's nation-leading 14-game winning streak and the Sooners' 18-game run against the Cyclones that dated to 1990. It was just Iowa State's second victory over Oklahoma since 1961, and the Cyclones (3-2, 1-1 Big 12) did it without their starting quarterback.
Kempt, the senior who had thrown just two passes in his career before Saturday, played because regular starter Jacob Park went on leave for undisclosed personal medical reasons late this week. The Cyclones remained confident, despite having lost 20 straight against ranked opponents. Iowa State's last win over a Top 25 team came against TCU in 2012. It was Iowa State's first road win over a top-5 team.
"We came in telling our whole team you have to believe for four quarters," Lanning said. "Believe you can beat a Top 5 team in the country. That's what we did today."
Baker Mayfield passed for 306 yards and rushed for 57 the Sooners (4-1, 1-1). It was Lincoln Riley's first loss as head coach.
The Cyclones gained 449 yards and got into a rhythm after struggling early.
Michigan State 14, at No. 7 Michigan 10: Brian Lewerke ran for a touchdown and threw for a score in the first half as the Spartans beat the Wolverines for the eighth time in the last 10 years. The Wolverines had the ball with a chance to drive for a go-ahead TD, but a heave from Michigan State's 37 as time expired hit the turf near the goal line.
The Spartans (4-1, 2-0 Big Ten) had never beaten Michigan eight times in a 10-year stretch in a series that dates to 1898.
Michigan (4-1, 1-1) could not overcome many mistakes, including five turnovers and several costly penalties. John O'Korn, replacing injured starter Wilton Speight, threw three interceptions in the second half.
No. 1 Alabama 27, at Texas A&M 19: Damien Harris ran for 124 yards and a touchdown, and Jalen Hurts had a touchdown pass and ran for another score to help Alabama remain undefeated.
The Aggies (4-2, 2-1 Southeastern Conference), who entered the game as 26 1/2 point underdogs, made the game interesting, but in the end freshman quarterback Kellen Mond was simply too inexperienced to help them topple a team as talented as Alabama.
Alabama (6-0, 3-0) had rolled past Vanderbilt and Mississippi by a combined score of 125-3 over the last two weeks, but got much more of a test from the young Aggies. Mond was 19 of 29 for 237 yards with a touchdown and an interception. He also ran for a touchdown and lost a fumble.
at No. 2 Clemson 28, Wake Forest 14: Quarterback Kelly Bryant threw for 200 yards and a touchdown before leaving the game because of an ankle injury as the second-ranked Tigers moved to 6-0 for a third consecutive season.
There was no immediate word on the severity of Bryant's injury. He left the game in the third quarter after Travis Etienne's one-yard touchdown run put Clemson ahead 21-0. Trainers looked at Bryant's ankle and took him into the sideline medical tent. Bryant tested his legs with a few short jogs once he came out and remained on the sidelines with teammates.
Bryant did not re-enter the game as Clemson (6-0, 4-0 Atlantic Coast Conference) beat the Demon Deacons (4-2, 1-2) for a ninth straight time.
No. 4 Penn State 31, at Northwestern 7: Trace McSorley threw for 245 yards and a touchdown while Saquon Barkley ran for two scores for the Nittany Lions. McSorley completed 25 of 34 passes. He threw a 10-yard touchdown to backup quarterback Tommy Stevens in the second quarter and added a five-yard TD run in the fourth.
Barkley scored on a 1-yard leap and 53-yard dash in the third quarter to make it 24-0. The Heisman Trophy candidate finished with 75 yards rushing after being held to minus-1 in the first half. Shaka Toney had two sacks, and the Nittany Lions (6-0, 3-0 Big Ten) came away with an easy victory.
No. 5 Georgia 45, at Vanderbilt 14: Nick Chubb ran for two touchdowns and 138 yards and the Bulldogs went on to win in a rout despite missing three players from the Bulldogs' stingy defense.
Georgia (6-0, 3-0 Southeastern Conference) continued its best start since 2012 when the Bulldogs reached the SEC championship. The Bulldogs also avenged a 17-16 loss to Vanderbilt last year. Georgia ran through and over Vanderbilt, piling up 423 yards. Sony Michel added 150 yards and a TD, while Elijah Holyfield scored his first career TD on a 15-yard run.
Vanderbilt (3-3, 0-3) lost its third straight to wrap up the toughest four-game stretch in school history against the Commodores' fourth consecutive ranked opponent.
at No. 8 TCU 31, No. 23 West Virginia 24: Kenny Hill evaded a defender in the backfield and lunged forward through two more for a three-yard touchdown run with 2:53 left and the Horned Frogs (5-0, 2-0) remained the Big 12's only undefeated team. Hill also threw a 45-yard touchdown pass and was on the receiving end of a 48-yard score.
Will Grier threw for 366 yards and three TDs for West Virginia (3-2, 1-1), including two long catch-and-run scores in a span of about 2 1/2 minutes late in the third quarter. It was tied at 24 after Grier hooked up with David Sills V on a 64-yard scoring play and then Ka'Raun White for a 76-yarder.
No. 9 Wisconsin 38, at Nebraska 17: Freshman Johnathan Taylor rushed for a season-high 249 yards and two touchdowns to lead a punishing ground game.
The Badgers (5-0, 2-0) beat the Huskers (3-3, 2-1) for the fifth straight time and took sole possession of first place in the Big Ten West.
Taylor, who had his second 200-yard performance in five games, carried 25 times while recording the third-most rushing yards ever by a Nebraska opponent.
at No. 10 Ohio State 62, Maryland 14: J.T. Barrett threw for three touchdowns and ran for another in the first half, and the Buckeyes (5-1, 3-0 Big Ten) had their most dominant defensive effort in nearly 60 years. The Terapins (3-2, 1-1) were held to 66 total yards — the fewest yards Ohio State had given up since yielding 60 against Indiana in 1960.
Barrett, a fifth-year senior and holder of most of the school's passing records, was 20 for 31 for 261 yards before taking a seat near end of the third quarter. Barrett threw scoring passes to Binjimen Victor, Austin Mack and Terry McLaurin.
at No. 12 Auburn 44, Mississippi 23: Kerryon Johnson rushed for a career-high 204 yards and three touchdowns and the Tigers (5-0, 3-0 Southeastern Conference) continued a recent tear with their third straight lopsided win over a league opponent. Johnson, who didn't play in the fourth quarter, has 11 touchdown runs during that hot streak.
The Rebels (2-3, 0-2) endured their second straight blowout in the state a week after losing 66-3 to No. 1 Alabama. This one was much closer, but not competitive.
No. 13 Miami 24, at Florida State 20: Malik Rosier threw a 23-yard touchdown pass to Darrell Langham with six seconds left as the Hurricanes (4-0, 2-0) ended a seven-game losing streak in the series. Rosier, who came into the game leading the Atlantic Coast Conference in passing efficiency, had a rough start as he completed only four of his first 16 passes. The junior found a rhythm in the second half and finished 19 of 44 for 254 yards and three touchdowns.
After Florida State (1-3, 1-2) took a 20-17 lead with 1:24 left on James Blackman' 20-yard pass to Auden Tate, Rosier drove Miami (4-0, 2-0) 75 yards in nine plays and 1:18. The junior found Langham in single coverage up the right sideline and he beat Tarvarus McFadden.
No. 16 Virginia Tech 23, Boston College 10: Josh Jackson threw for 322 yards and a touchdown and the Hokies (5-1, 1-1 ACC) bounced back from a loss to defending national champion Clemson. Sean Savoy had nine catches for 139 yards and a score after No. 1 receiver Cam Phillips went out with an apparent leg injury in the first quarter.
Travon McMillian ran 17 times for 88 yards, including a 23-yard touchdown that gave Virginia Tech a 17-3 lead midway through the second quarter. With 11 points — three field goals and two extra points — Joey Slye became the school's career scoring leader.
Anthony Brown completed 13 of 30 passes for 166 yards for BC (2-4, 0-2). He also caught a touchdown pass on a halfback option from former quarterback Jeff Smith.
LSU 17, at No. 21 Florida 16: Danny Etling threw a short touchdown pass in the second half and the Tigers rebounded from a stunning home loss to Troy last week to beat the Gators. Louisiana State (4-2, 1-1 Southeastern Conference) moved the ball well early with jet sweeps and then pounded it between the tackles late, doing just enough to upend Florida (3-2, 3-1).
The difference was Florida's usually stout kicking game. Eddy Pineiro missed the first extra point of his career in the third quarter and never got a chance to atone for it. He had made 45 in a row.
No. 21 Notre Dame 33, at North Carolina 10: Josh Adams ran for 118 yards, including a 73-yard touchdown, and Deon McIntosh added 124 yards rushing and two scores for the Fighting Irish (5-1), who played without starting quarterback Brandon Wimbush because of a right foot injury. Notre Dame finished with 487 yards, 341 coming on the ground.