The Clippers had a 17-point advantage entering the fourth quarter, but the Pacers cut the deficit to two after Lavoy Allen made a jumper with two minutes left. The Pacers outscored the Clippers at the top of the fourth quarter, 18-6.
The Clippers led by as many as 15 points in the first quarter, saw their lead erased in the second, then retook control of the game in the third quarter, pushing their advantage to as much as 20 before the Pacers made their final run at the end of the game.
The Clippers had good ball movement, finishing with six players in double figures and 25 assists on their 42 field goals. They outshot the Pacers, 47.7% to 39.3%, and out-rebounded them, 50-43.
Jamal Crawford, who had his first career ejection in 15 seasons on Monday, finished with 18 points on seven-for-12 shooting Wednesday. Chris Paul had 17 points and 15 assists. Blake Griffin had 17 points and 10 rebounds. J.J. Redick had 16 points on seven-for-11 shooting. DeAndre Jordan had 19 rebounds, three blocked shots and 12 points. Matt Barnes added 11 points.
The win lifted the Clippers (16-5, 8-2 on the road) to fifth place in the Western Conference.
The Pacers (7-15), who lost their sixth consecutive game, were led C.J. Miles, who had 30 points, six assists and two rebounds.
The Clippers, finish their three-game trip against Washington on Friday and Milwaukee on Saturday.